International Graduate Program Medical Neurosciences

Pain – mechanisms and management

Contact

Prof. Dr. Halina Machelska
t.: 8445-3851
halina.machelska(at)charite.de

Description

The course is organized in the frame of the International Graduate Program “Medical Neurosciences”, and it is held in English www.medical-neurosciences.de/en/. It addresses basic as well as unconventional aspects of pain and its treatment. It covers multiple pain aspects such as anatomy, physiology and pharmacology of the sensory nervous system, physiology and pathology of acute and chronic pain, endogenous pain modulation, genetic and psychological aspects of pain, gender differences in pain and its inhibition, current and novel pain therapies, ethical guidelines of studies in animals and humans. The course is based on lectures, literature analyses and practical demonstrations of pain testing in rodents and electrophysiological methods. It involves active student participation.

The major goals are:

  • to address physiological and pathological aspects of pain;
  • to see pain as a disease and not only as a symptom;
  • to be able to present articles in a concise way to other students/teachers and gain skills in giving talks;
  • to objectively analyze manuscripts as to the methods, statistics, relevance of the data, the quality of the introduction and discussion; and
  • to be constructive in your criticism by suggesting options for improvement.

Additional information:

Target audience: M.Sc., Ph.D., medical students
Date & Time: both semesters, 3 hrs per week, day and time to be chosen by students
Location: Pain Research Laboratory
Klinik für Anaesthesiologie mit Schwerpunkt operative Intensivmedizin
Campus Benjamin Franklin
Charité - Universitätsmedizin Berlin
Krahmerstr. 6
Room IV/1.

Opioid receptor expression in neuronal tissues – a practical course

Contact

Dr. Melanie Busch
t: 8445-2131
melanie.busch(at)charite.de

Description

The course is organized in the frame of the International Graduate Program “Medical Neurosciences”, and it is held in English www.medical-neurosciences.de/en/. Students analyze neuronal tissues such as cerebellum, hypothalamus, spinal cord, dorsal root ganglia, and peripheral nerves for mu-opioid receptor expression. We work in a group but each student performs all experiments independently. Tissues are used to isolate total RNA or protein. The students will learn how to synthesize cDNA, to perform conventional RT-PCR and real-time LightCycler PCR. Protein expression is analyzed by Western Blotting.

Additional information:

Target audience: B. Sc., M.Sc., medical students
Date & Time: winter semesters, two weeks in block, daily 9 am - 5 pm; day to be chosen by students
Number of participants: max. 4
Location: Pain Research Laboratory
Klinik für Anaesthesiologie mit Schwerpunkt operative Intensivmedizin
Campus Benjamin Franklin
Charité - Universitätsmedizin Berlin
Krahmerstr. 6
Room IV/1 and lab spaces.

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