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The major research topics in our Department are translational research on mechanisms and therapeutic approaches in acute and chronic pain with a focus on the opioid system, as well as emergency medicine, educational research, and the history of Anesthesiology. Our approaches include mathematical modeling, preclinical experiments, and clinical studies. Our laboratory features molecular, biochemical, cellular, electrophysiological, and behavioral methods. Clinical studies are performed in our pain clinic, perioperative setting, and intensive care unit. We are funded by the German Research Foundation (DFG), Federal Ministry of Education and Research (BMBF), and European Union. We mentor Bachelor, Masters, PhD, and MD students.